Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 250mg | ||||
360 pill | 250mg | AUD454.29 | AUD1.26 | |
180 pill | 250mg | AUD244.25 | AUD1.35 | |
120 pill | 250mg | AUD177.35 | AUD1.48 | |
90 pill | 250mg | AUD143.12 | AUD1.59 | |
60 pill | 250mg | AUD104.23 | AUD1.73 | |
30 pill | 250mg | AUD59.11 | AUD1.96 | |
Dosage: 500mg | ||||
90 pill | 500mg | AUD155.57 | AUD1.73 | |
60 pill | 500mg | AUD108.89 | AUD1.82 | |
30 pill | 500mg | AUD59.11 | AUD1.94 |

Chloramphenicol Description
Overview of Chloramphenicol
Chloramphenicol is a broad-spectrum antibiotic that has been used for many years in the treatment of various bacterial infections. It is effective against a wide range of bacteria, including those responsible for serious infections such as typhoid fever, meningitis, and eye infections. Due to its potency, chloramphenicol is often reserved for cases where other antibiotics are ineffective or contraindicated. It works by inhibiting bacterial protein synthesis, which ultimately prevents bacteria from multiplying and spreading.
How Chloramphenicol Works
Chloramphenicol interferes with the peptidyl transferase activity in bacterial ribosomes. This action blocks the formation of peptide bonds during protein synthesis. As a result, bacteria are unable to produce essential proteins needed for growth and survival. The unique mechanism of action makes chloramphenicol potent against many bacterial strains, including some multidrug-resistant ones. However, its ability to affect mitochondrial protein synthesis in human cells can lead to adverse effects, which warrants careful use.
Usage and Administration
This medication is available in various forms, including tablets, eye drops, and injections. The mode of administration depends on the specific infection being treated. For systemic infections, oral or injectable forms are usually prescribed. The dosage and duration of treatment are determined by the type and severity of the infection, as well as individual patient factors. It is important to follow the healthcare provider’s instructions strictly and not to self-medicate, as improper use can increase the risk of side effects and antibiotic resistance.
Potential Benefits of Chloramphenicol
One of the main advantages of chloramphenicol is its broad-spectrum activity. It is particularly useful in resource-limited settings or in cases where other antibiotics have failed. Its effectiveness in treating severe infections, like meningitis caused by resistant bacteria, makes it a valuable drug in certain clinical situations. Additionally, chloramphenicol’s ability to rapidly cross the blood-brain barrier makes it highly effective for central nervous system infections.
Risks and Side Effects
While chloramphenicol can be highly effective, it also carries significant risks. The most serious adverse effect is aplastic anemia, a rare but potentially fatal condition where the bone marrow fails to produce enough blood cells. This risk limits its use to specific cases and calls for close monitoring during therapy. Other side effects include allergic reactions, gastrointestinal disturbances, and gray baby syndrome—a condition affecting newborns characterized by circulatory collapse, which can be fatal if not recognized early. Because of these risks, chloramphenicol should be used with caution and under strict medical supervision.
Precautions and Considerations
Patients taking chloramphenicol should be monitored regularly through blood tests to detect any early signs of blood dyscrasias. Its use is generally contraindicated in pregnant women and children under two years old due to the risk of gray baby syndrome and other complications. It is essential to inform your healthcare provider about any other medications being taken, as chloramphenicol can interact with certain drugs, increasing the risk of adverse reactions.
Conclusion
Chloramphenicol remains a potent antibiotic with valuable clinical applications. Despite its effectiveness, its potential for serious side effects necessitates careful consideration and usage under medical supervision. When prescribed appropriately, it can be an important weapon against challenging bacterial infections, especially in cases where alternatives are limited. Proper monitoring during therapy is crucial to minimize risks and ensure maximum benefit from this medication.
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