Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 1% | ||||
5 tube | 1% | AUD79.33 | AUD15.87 | |
4 tube | 1% | AUD74.67 | AUD18.67 | |
3 tube | 1% | AUD65.33 | AUD21.78 | |
2 tube | 1% | AUD49.77 | AUD24.88 | |
Dosage: 5% | ||||
5 tube | 5% | AUD194.47 | AUD38.90 | |
4 tube | 5% | AUD168.02 | AUD42.01 | |
3 tube | 5% | AUD140.01 | AUD46.68 | |
2 tube | 5% | AUD108.89 | AUD54.44 |

Fluorouracil Description
Description of Fluorouracil
Fluorouracil is a widely used chemotherapeutic agent primarily employed in the treatment of various types of cancer. It belongs to the class of antimetabolites, which work by disrupting the synthesis of DNA and RNA, ultimately inhibiting the growth of malignant cells. Fluorouracil is often prescribed for cancers such as colorectal, breast, stomach, pancreatic, and skin cancers. Due to its effectiveness, it has become a staple in both outpatient and inpatient chemotherapy regimens.
How Does Fluorouracil Work?
This medication mimics the natural pyrimidine bases that are essential for cell division. When incorporated into the cellular machinery, Fluorouracil interferes with thymidylate synthase, an enzyme necessary for DNA synthesis. The result is a blockade in DNA replication, which triggers cell death, especially in rapidly dividing cancer cells. This targeted action makes Fluorouracil a potent agent for controlling tumor growth, although healthy cells that divide quickly can also be affected, leading to some of its side effects.
Administration and Dosage
Fluorouracil can be administered in several forms, including intravenous injections, topical creams, and sometimes as part of combination therapy. The exact dosage depends on the type and stage of cancer, patient’s overall health, and other factors. Typically, doctors establish a precise treatment schedule to maximize efficacy while minimizing adverse effects. Regular monitoring during therapy is essential to adjust dosages if needed and to manage potential complications.
Possible Side Effects
Like many chemotherapy drugs, Fluorouracil may cause a range of side effects. Common adverse reactions include mouth sores, nausea, vomiting, diarrhea, and loss of hair. Some patients also experience bone marrow suppression, leading to a decreased number of blood cells, which increases the risk of infections and bleeding. Skin reactions such as redness, peeling, or rash can occur especially when topical formulations are used. Serious but less common side effects include heart problems and neurological effects. It is vital to report any unusual symptoms to the healthcare provider promptly.
Precautions and Considerations
Before starting treatment with Fluorouracil, a thorough medical evaluation is necessary. Patients with pre-existing conditions such as liver or kidney problems may require dose adjustments. Pregnant or breastfeeding women should avoid using this medication, as it can harm the fetus or infant. Patients should inform their healthcare provider about all current medications to avoid potential interactions, especially with drugs that can affect blood cell counts or interfere with chemotherapy efficacy.
Storage and Handling
Fluorouracil should be stored in a secure place, away from direct sunlight and out of reach of children. Proper handling and disposal are essential to prevent accidents, especially with injectable forms. Healthcare professionals typically administer the medication in a clinical setting, ensuring proper techniques are followed to minimize exposure and contamination.